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Generalizing predictions to unseen sequencing profiles via deep generative models

Despite its therapeutic potential, the clinical translation of OA is hindered by poor aqueous solubility, limited cutaneous permeation, and rapid systemic clearance, which compromise bioavailability in topical applications [13]

Enhancing glutathione availability Boosting glutathione levels can have positive effects on overall immune function and balance

Collectively, these preclinical studies underscore the promise of engineered live bacterial therapeutics for HCC treatment and provide references for translational development

Activation of NF2 can promote the downregulation of E3 ubiquitin ligase CRL4 DCAF1 , suppress Lats1/2 degradation in the hippocampal pathway, thereby promote YAP phosphorylation [227]